Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MMEL1 All Species: 20.91
Human Site: S551 Identified Species: 41.82
UniProt: Q495T6 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q495T6 NP_258428.2 779 89367 S551 L K V G A Q R S L R K L R E K
Chimpanzee Pan troglodytes XP_001150860 781 89158 S553 L K V G A Q R S L R K L R E K
Rhesus Macaque Macaca mulatta XP_001105708 750 85452 L523 K F S Q S K Q L K K L R E K V
Dog Lupus familis XP_546737 807 92419 S579 L K A G A Q R S L K K L R E K
Cat Felis silvestris
Mouse Mus musculus Q9JLI3 765 88681 S537 L K N N A Q R S L K K L R E K
Rat Rattus norvegicus P0C1T0 774 89178 S546 L K N N A Q R S L K K L R E K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001233077 749 86047 S521 L R A G A Q K S L K K L R E R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_689191 755 86752 G527 L A A S A Q K G H K K L R E P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_511056 849 96515 R624 W E S E K M L R L L R Q P V D
Honey Bee Apis mellifera XP_392502 776 89056 E551 Y D A Y H N L E K L R K P V D
Nematode Worm Caenorhab. elegans O16796 848 97043 F621 V W M Q S R E F Q K L T K P F
Sea Urchin Strong. purpuratus XP_781407 763 86739 K539 W S A N E N L K K L R E E V D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.9 50.8 82.6 N.A. 77 77.6 N.A. N.A. 66.2 N.A. 59.9 N.A. 39 40.5 35 38.1
Protein Similarity: 100 97.1 72 89 N.A. 88.6 88.8 N.A. N.A. 81.6 N.A. 77.6 N.A. 55.9 59.8 54.1 58.5
P-Site Identity: 100 100 0 86.6 N.A. 80 80 N.A. N.A. 66.6 N.A. 46.6 N.A. 6.6 0 0 0
P-Site Similarity: 100 100 33.3 93.3 N.A. 86.6 86.6 N.A. N.A. 93.3 N.A. 60 N.A. 20 6.6 40 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 42 0 59 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 25 % D
% Glu: 0 9 0 9 9 0 9 9 0 0 0 9 17 59 0 % E
% Phe: 0 9 0 0 0 0 0 9 0 0 0 0 0 0 9 % F
% Gly: 0 0 0 34 0 0 0 9 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 9 0 0 0 9 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 9 42 0 0 9 9 17 9 25 59 59 9 9 9 42 % K
% Leu: 59 0 0 0 0 0 25 9 59 25 17 59 0 0 0 % L
% Met: 0 0 9 0 0 9 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 17 25 0 17 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 17 9 9 % P
% Gln: 0 0 0 17 0 59 9 0 9 0 0 9 0 0 0 % Q
% Arg: 0 9 0 0 0 9 42 9 0 17 25 9 59 0 9 % R
% Ser: 0 9 17 9 17 0 0 50 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % T
% Val: 9 0 17 0 0 0 0 0 0 0 0 0 0 25 9 % V
% Trp: 17 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _